During a promotional interview for the movie with website Collider.com, she expressed pride in working on an independent project: "It's something I've been trying to do for years and years [...] It's almost like my first movie in a weird way, cause it's my first movie in this world, which is a world I've been trying to break into.[I've wanted] to be around filmmakers that are trying new things and not part of the system, so to speak, and they're doing things on their own terms." In 2012, Winstead and Topher Grace appeared in The Beauty Inside, an "interactive social film".Winstead got a chance to lampoon horror scream queens when Tonight Show host Jay Leno, unaware of who she was, knocked on her front door and included her in a comedy segment spoofing horror films.She appeared in Emilio Estevez's Bobby, a 2006 film depicting the last hours of Robert F. In 2007 Winstead appeared in a pair of high-profile event films.
He awakes each day with a different appearance; Winstead appeared as Leah, Alex's love interest.
Nevertheless, it proved a delight for Winstead, who once dreamed of being a dancer. Reviewer Mike Martin wrote, "Winstead infuses every moment with an amazing amount of charm".
and the film was released in late 2010, to critical acclaim but poor box office returns.
Winstead's performance was well received generally, and earned her a Teen Choice Awards nomination for Choice Actress Action.
which followed a group of scientists who discover an alien buried deep in the ice of Antarctica, realizing too late that it is still alive. Kate Lloyd, a character she based on her sister, a neurologist.